Participants will be sent three FFPE blocks representing a particular cancer type, depending on the exercise, paired with clinical vignettes. The laboratories are asked to assess the specimen, and provide all necessary testing required for treatment (IHC, NGS, etc). Following testing, laboratories are asked to provide the CPQA-AQCP with a final report for each case analogous to a report that would be provided in a similar clinical scenario.

Evaluation will be made based on multiple factors: the accuracy of results compared to the reference result, the timeliness based on turnaround time between sample delivery and report submission, the interpretation of the results and finally the overall the clarity of reporting. The evaluation committee will be comprised of molecular pathologists and medical oncologists from various Canadian institutions and tailored to each exercise. Individualized feedback from the clinician assessor committee will be provided to each participant in a report comparing their performance to other Canadian labs.